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Fifty-eight studies were excluded with reasons.
Finally, 16 studies were excluded with reasons, and 41 RCTs were included in this systematic review.
Forty-three studies were excluded with the following reasons: no GP data (n = 31), not an RCT (n = 6), meta-analyses or literature review (n = 3), clinical trial (n = 3) and two articles could not be retrieved.
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Then in the remaining 13 studies, we reviewed the full text and 5 studies were excluded including 1 with non T2D subjects, 3 with incomplete data and 1 with duplicated crowd.
Duplicate studies were excluded and publications with overlapping study populations, the publication with the largest number of subjects was included.
Overall, 9 studies were excluded for redundancy with other included studies, 5 as containing only neutropenic patients, and two as containing only palliative patients.
Access to treatment or screening services, immunisation uptake, child abuse or domestic violence studies were excluded unless reported with a social determinant and child health outcome.
Second, three of the studies reviewed [69, 71, 77] examined rehydration in combination with another placebo treatment (studies were excluded if fluids were co-administered with another experimental treatment).
Ultimately, 17 studies were excluded, and 12 were included with a total of 1,331 patients [23],[23]-[23].
Ultimately, 17 studies were excluded, and 12 were included with a total of 1,331 patients [ 23],[ 28]-[ 38].
After assessing the titles and abstracts, 157 studies were excluded because of non-compliance with the inclusion criteria.
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