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Heterogeneity among studies were estimated by the Cochran's Q-statistic and I 2 tests [ 21].
The individual HRs of the 11 included studies were estimated using the methods reported by Parmar et al (1998).
Characteristics of respondents included in the analysis and all respondents from the 35 included studies were estimated using robust SEs, clustered by country, and probability sampling weights.
Human health risks in these studies were estimated as lifetime cancer risk, and calculated using exposure assumptions developed for the U.S. as whole, not the Navajo specifically.
The effective sample sizes of cluster randomised studies were estimated based on an assumed intra-cluster correlation (ICC) of 0.04 [ 17, 20].
Indeed, regarding standardized risk of bias assessment, only 29% of included studies were estimated as having a low risk of bias whereas 22% were rated as of high risk.
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All observational studies were estimating overdiagnosis adjusted for annual underlying incidence increases.
This assumes that different studies were estimating different intervention effects and partly explains the heterogeneity between studies.
Together with studies published in Chinese language, more than 300 ARTP case studies are estimated to be currently available.
Heterogeneity across studies was estimated by calculating I2.
Heterogeneity of studies was estimated by calculating I2 and Cochrane p values.
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