The loading mechanisms used in previous studies were either distributed or point loads.
All included studies were either observational (prospective or retrospective), clinical cohorts, or population surveys.
The remaining studies were either non-randomised (n = 1) or uncontrolled clinical trials (n = 3).
Transparent wood (TW) structures in research studies were either thin and highly anisotropic or isotropic and weak.
However, those studies were either performed in small populations or complete paralysation of the pronator quadratus was reached by injecting lidocaine into the muscle.
Despite these first important findings, the few listed studies were either correlative or only covered a rather short follow-up time.
Another aspect was that the cases included in these studies were either diagnosed with class II division 1 or bi-maxillary proclination.
Among surveys and reviews, most syntheses of multiple, independent studies were either entirely qualitative or used overly simplistic approaches to data aggregation.
Most previous studies were either regional in extent or relied on arbitrary definitions of cities that varied across regions.
Animals used for subsequent studies were either young adults (2 6 months of age) or older animals (14 months of age) fed dox on the regime described above.
However, currently available studies were either restricted to single antigenic epitopes or a subgroup of patients with a certain HLA type.
