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For these studies, we utilized the crystal structure of the ternary complex of PFN1 in complex with actin and PLP (PDB code: 2PAV) www.rcsb.org/structure/2PAV 2PAV
In our initial studies, we utilized this VPg-nonanucleotide substrate to determine the presence and levels of unlinkase activity.
Therefore in the present study, as in prior in vivo studies, we utilized human BMP-7 in our mouse models.
In our studies, we utilized two primary therapies- CsA and allochimeric molecules to achieve distinctive tolerant states, which in turn elicited different responses of TCR repertoire.
For these studies, we utilized the MP-specific T-cell hybridoma P1D6, which produces IL-2 when stimulated by DCs presenting a peptide fragment of MP98 in an MHC II-restricted fashion [12].
For these studies, we utilized THP-1 derived cell lines that have been transduced with recombinant retrovirus expressing shRNA that "knock down" expression of the inflammasome components, ASC or NLRP3 [42], [42].
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In this study, we utilized genotyping data to calculate individual ancestry and examined whether primary and secondary cytogenetic abnormalities differed by high and low African ancestry.
In the current study, we utilized several screening methods to find the most operative BS-producer to be properly employed in food industry sectors.
In the current study, we utilized a two-chamber co-culture system to partly mimic the crosstalk between cancer cells and macrophages in OSCC tissue.
In the present study, we utilized both in vitro and in vivo models to investigate the protective effect of BBR against MI/R-induced cardiac damage.
In this study, we utilized PBMCs from cynomolgus macaques with naturally-controlled SIV infection as a model to investigate the characteristics of latent infection.
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