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However, the type of approach taken by these studies suffers from some significant drawbacks.
However, the reproducibility of the studies suffers in terms of standardization regarding tumor specimen (primary tumors or metastases), methodology (RT-PCR, Western-blot or immunohistochemistry), and the evaluation of the IHC-staining.
Despite coexistence, hybridization of Iberian barbels in areas of species overlap has been hypothesized based on specimens with intermediate phenotypes [ 21, 39– 41] and mtDNA polyphyly [ 42], but inference of hybridization in these studies suffers from species identification problems [ 26] and circularity.
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Gold's studies suffered.
People used to leave the village as their studies suffered without electricity.
These studies suffer, however, from endogeneity issue.
However, most of the studies suffer from different deficits.
Most of the studies suffer from the methodological deficiencies discussed above.
Otherwise, withdrawal-based studies suffer similar threats to validity as intervention studies.
Not only have previous studies suffered from design limitations, they also reached contradictory conclusions.
Structure-based design studies suffer from the lack of available protein structures at atomic resolution.
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