Exact(1)
This is also reflected in altered European guidelines for drug formulation bio-equivalence studies, specifying that for narrow therapeutic index drugs the acceptance interval for AUC can be tightened to 90.0 111.1 % [ 1].
Similar(59)
These studies specify that PLLA nanofibers loaded with 20 and 40 wt% of CQ could serve as a potential candidate for bone tissue engineering applications.
Twenty nine studies specify that clinical workflow must be taken into consideration to optimize the integration of electronic health records into the routine clinical practice [ 3, 4, 7, 15, 24, 26- 30, 43- 47, 48, 48, 51- 560 61, 61, 673 69, 73- 75].
X-ray diffraction studies specify that the crystallite size value, minimize with a rise in co-deposited particle content.
For the behavioral intervention, CBT was used in 11/23 (48 %) (one study used family CBT), relaxation was used in 8/23 (35 %) (half of these studies specified that PMR was used for the relaxation therapy), and biofeedback was used in 5/23 (22 %) of the studies.
Five studies specified that they used computer randomisation.
Entry criteria for all studies specified that A1C be >7.0% at enrollment.
A further three studies specified that ulcers involving tendons, joint spaces and/or bone were excluded.
Most studies included children aged 2 6 years and only four studies specified that children below 2 years were included.
Definitions of violations offered in two of the seven studies specified that violations were not intended to harm [ 40, 43].
Two analytical studies specified that expert support must be given to promote adoption of the systems [ 7, 76].
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