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Some studies revealed normal cholesterol contents (Jansen et al., 2000; Lomnitski et al., 1999; Han et al., 2003) and turnover in brain, on the other hand, other studies showed reduced cholesterol level (Levi et al., 2005).
The electrophysiological studies revealed normal motor and sensory nerve conduction velocities along with reduced amplitudes of compound motor action potentials and normal amplitudes of sensory nerve-action potentials.
Biochemical studies revealed normal values for serum calcium, phosphorus, 1,25(OH)2D3 and bone-specific alkaline phosphatase (ALP), while PTH was slightly increased.
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Despite clinical parkinsonism, dopamine transporter PET and single-photon emission computed tomography studies reveal normal dopamine uptake (Brashear et al., 1999; Zanotti-Fregonara et al., 2008) and, unfortunately, patients with rapid-onset dystonia parkinsonism do not respond to levodopa or pallidal deep brain stimulation (Deutschlander et al., 2005; Kamm et al., 2008 b ).
An initial echocardiographic study revealed normal cardiac function but failed to give an accurate LVEF.
Exercise stress testing of the workers studied revealed normal heart reaction to the increased need for oxygen, while sinus tachycardia was detected in all the participants.
This diagnosis was amended to exudative polymorphous vitelliform macular dystrophy two years later when he underwent electrophysiological studies which revealed normal rod electroretinography (ERG) but abnormal flicker ERG with b-wave delay and abnormal electro-oculography (EOG) (Fig. 1a).
We did not perform ACTH stimulation tests in this experiment, mainly because pre-anesthetic testing in the study dogs revealed normal adrenal function.
A number of studies have also revealed normal probabilistic, associative, or motor sequence learning in participants with PD at baseline.
These studies revealed that normal tissue fibroblasts variably express at least two functionally distinct activities in modulating cancer cell proliferation.
While light microscopic studies revealed a normal retina, they are not optimal for assessing the integrity of outer retina component such as outer segment discs and the intricate relationship between outer segments and retinal pigment epithelial cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com