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As some drugs may not cause changes in core battery parameters such as tidal volume (Vt), respiratory rate (RR) or minute ventilation (MV), including measurements of respiratory mechanics in safety pharmacology studies represents an opportunity for design refinement.
Although it is certainly not an exhaustive list of all possible methods of conveying this information to the user, this series of studies represents an important first step in determining whether providing this information is useful.
Therefore attrition in the studies represents an important confounder.
As opposed to candidate gene-association studies where genes are chosen, linkage studies represents an unbiased approach and are not limited by an incomplete understanding of disease pathogenesis.
The availability of genetic material from participants in large epidemiological studies represents an invaluable resource for exploring genetic and environment influence on disease risk.
Although outside the scope of this study, investigating the cause of this incongruence between our and other studies represents an important step towards resolving this node in the percomorph tree of life.
Similar(54)
Using results from published studies represents a practical solution.
Her studies represent an area of overlap of neuroscience, psychology, philosophy, art history and visual studies.
These two studies represent an exciting new development in iPSC research.
Modelling studies represent an alternative to randomized controlled trials.
These studies represent an important step towards an improved understanding of drug resistance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com