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Then again, participants in the major PrEP studies received free condoms and regular sexual-health counselling.
These studies received ethical approval from the University of Alberta Human Research Ethics Board.
Seventeen studies received a Jadad score of ≥3 and were considered high-quality studies.
But several of these studies received some funding from the pharmaceutical companies marketing these drugs to veterinarians and pet owners.
Control animals in the immunoblotting studies received a 50-ml sipper tube containing tap water in lieu of 20% alcohol.
Some of the rats in the studies received all three compounds and some received only one.
Half the patients in both studies received an intravenous antibiotic, ceftriaxone, for a month, followed by oral doxycycline for 60 days; the others received dummy medications.
Both studies received approval by the Medical Ethics Committee of UMCU.
None of the studies received external funding and no clear sources of bias were identified.
Data were collected through a questionnaire and include demographics, associated diseases, culture results, laboratory studies, received treatments, and final outcome.
All studies received ethical approval from either King's College Hospital or the Joint from South London and Maudsley and Institute of Psychiatry Research Ethics Committees.
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