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In these studies, progression and lingering are defined through an examination of the average maximal speed distribution in segments between arrests.
In both studies, progression was evaluated by independent review using RECIST criteria (primary end point) and also by investigator assessment.
In a number of studies, progression to dementia has been delineated by change from a global CDR of 0.5 (questionable dementia) to a global CDR of 1.0 (mild dementia) or higher [ 36, 37].
In previous studies, progression from IGT to diabetes has varied between 5 and 6% per year (1, 16, 17) and from IFG to diabetes between 3 and 6% per year (16, 17).
In these latter three studies, progression of glycemia beyond a year was slower with thiazolidinedione therapy compared with either placebo or any of the active comparators (7, 8, 13), suggesting a possible modification of the underlying disease process.
In some studies, progression was implemented through increasing the number of repetitions of an exercise, not the intensity or load, which will lead to limited improvements, particularly in regard to strength and power.
Similar(52)
We studied progression of atrophy in six lobar brain regions in AD, MCI and control subjects.
Meetings with the site collaborators and data collectors are occurring every month to ensure study progression.
There was no correlation between GRAS-DK score and age, study progression, or extracurricular activity.
It would also be interesting to study progression of atrophy over multiple time points.
bFor the purpose of this study, progression will be defined as the first progression from initial therapy (as defined above).
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