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Compared to their application in broader public health studies, other methods such as K-functions and spatial scan statistics were also not common in injury studies.
In different studies other methods have been put forward; however, these methods cannot compete with the thread rolling test in simplicity, execution time and cost.
In future studies, other methods, such as prescription refill records, could be considered to evaluate general trends within large sample sizes.
In the absence of direct comparisons from head-to-head randomized controlled studies, other methods for CER can be utilized, such as an indirect treatment comparison (ITC), mixed treatment comparison, or meta-regression [ 7].
In most cases, uniaxial or biaxial tensile tests were used, while in a smaller number of studies other methods, such as opening angle, bulge inflation, and inflation-extension tests, were used.
In such situations where estimating ρ B is difficult, application of two generalised URMAs may be the most appropriate option available (Table 3), although specifically for diagnostic studies other methods may also be valuable [ 21].
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While we used the proxy good approach in this study, other methods exist and these may result in quite different estimates [ 12].
Methods that were used for causality assessment varied and included the Naranjo algorithm [ 55] (18 studies), WHO definition [ 4] (6 studies), Karch and Lasagna method [ 56] (2 studies), or other methods (6 studies).
The doses of medication were selected to produce a moderate effect on gastric emptying based on prior studies utilizing other methods for studying gastrointestinal transit [ 7, 8].
Nine studies also undertook a site visit or observation, six studies performed an additional document review, and three studies included other methods.
Other definitions used included authors' own (n = 8, 11% of studies) and other methods or methods unclear (n = 10, 14% of studies).
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