Sentence examples for studies inactivation of from inspiring English sources

Thus, based on these studies, inactivation of the p53 pathway by the KSHV virus lies in the pathogenesis of this incurable malignancy.

In those studies, inactivation of the M. tuberculosis secA2 gene, which encodes a virulence-associated protein secretion system, enhanced the apoptosis of infected macrophages and increased priming of antigen-specific CD8+ T cells in vivo.

In both studies, inactivation of both tardbp and tardbpl (the latter either by gene disruption by ZFNs or by knockdown) resulted in a severe phenotype and early lethality, although the phenotype of double heterozygotes has not been reported and might more closely resemble the ALS genotype (if due to haploinsufficiency) and perhaps the (partial) knockdown phenotype.

In this study, inactivation of Escherichia coli (E. coli) was investigated in Na2SO4 electrolyte using BDD anode.

In this study, inactivation of the Prn gene significantly reduced colonization of both the trachea and lungs of mice (Fig. 2).

Based on results of previously published experiments utilizing mutS+ strains [20], Pol I and PolC are required for the vast majority of UV-induced mutagenesis: in this study, inactivation of dinB failed to impact significantly on the frequency of mutations induced by UV irradiation [20].

The criterion used for virucidal activity of the biocide was a four log10 reduction in this study (inactivation of 99.99%).

Second, in the current study, inactivation of both Th1 and Th17 cells improved insulin resistance (Figs 3D, E and 6D and E).

Use of pre-pulses is not new in the study of mechanosensitive channels and it has been used to study inactivation of MscS (Akitake et al., JGP 2005) and to show that "the availability of MscS depends on both the rate of pressure application and the amplitude of prepulse pressure".

The reduction of Apaf-1 expression in melanoma biopsies observed in our study is in agreement with previous studies demonstrating inactivation of Apaf-1 in melanoma cell lines (Soengas et al, 2001).

Our formerly published experimental results of studies on inactivation of Bacillus subtilis As 1.173 spores by high hydrostatic pressure and heat using design of experiments showed that the optimum process parameters for a six log-cycle reduction of spores of B. subtilis were obtained as: pressure, 576.0 MPa; temperature, 87 °C; and pressure holding time, 13 min.