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Genome-wide association studies have nominated many genetic variants for common human traits, including diseases, but in many cases the underlying biological reason for a trait association is unknown.
These studies have nominated regions of distal fallopian tube mucosa exhibiting stabilized p53 protein, termed "p53 signatures", and occult non-invasive intraepithelial serous carcinomas identified in prophylactic salpingo-oophorectomy specimens of BRCA1 mutation carriers as candidate precursors of invasive ovarian and/or pelvic serous carcinomas.
Nonetheless, recent genetic studies have nominated about 20 loci that may modify AO or progression of HD.
For example, recent studies have nominated the sepiapterin reductase gene (SPR) as the most likely candidate in the PARK3 region (71).
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Several studies in vivo as well as in vitro have nominated immunoglobulin G (IgG) isolated from ALS patients as an active contributor to disease onset and progression.
He could have nominated himself".
I have nominated Simon Silver to review it and have only brief remarks of my own.
George Bush has nominated Robert Gates to replace Donald Rumsfeld.
"Every time we've nominated a moderate, we've lost.
Daniel Craig has nominated him as his successor as 007.
But dissidents had nominated their own candidate to challenge Mr. King.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com