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In a recent GWAS study, one SNP in the FTO gene, which has been associated with mean BMI and obesity in previous studies, displayed significant association with BMI variability.
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The concentrations of less than 10% of the measured metabolites in the current study displayed significant differences of 2-fold or greater when comparing T2DM vs. non-diabetic subjects, and these metabolites might be some of the strongest biomarkers of metabolic health status.
The remaining three species in our study displayed significant foot allometry, where the degree of interdigital webbing increased during growth (Table 2; Figure 2, Figure 3).
Seven loci designated p4, p7, p16, p18, p25, p46, and p80, as well as the overall pattern for all 19 loci scored in the study, displayed significant trends for black hawthorn flies to become more 'snowberry-like' in their frequencies with geographic proximity to Yakima (Table 1, Fig. 4).
These murine findings are corroborated by a pediatric OI cohort study, displaying significant progressive decline in pulmonary function and restrictive pulmonary disease independent of scoliosis.
MTL-1 also indicates long duration of action in time course study and displayed significant seizure protection up to 6 h of drug administration.
Title: The 102 traits in this study that displayed significant sex-specific phenotypic values (q <0.05).
Second, in our study, most populations displayed significant deficit of heterozygotes at several loci and significant monolocus FIS estimates were widely distributed across loci.
This study population also displayed significant interference in daily life, school attendance and emotional well-being.
These infants were significantly younger than the remainder of the study populations and displayed significant resistance to insulin and persistent hyperglycemia despite insulin infusions, resulting in a clinical decision to reduce the dextrose concentration of their parenteral nutrition infusions.
DOI: http://dx.doi.org/10.7554/eLife.05033.008 Consistent with the well-established presence of regulatory uORFs in their 5′-UTRs, this genome-wide analysis identified four previously extensively studied mRNAs that displayed significant translational upregulation: ATF4, ATF5, CHOP, and GADD34,.
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