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Failure rates of all types of sterilization failures are estimated in 0.9% [12] but there is uncertainty about specific failure rates for Essure® due to either short follow-up studies, discrepancy between study results, or lack of information on follow-up or on accomplished protocol [13, 14].
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A number of studies report discrepancies in the values obtained from patients and the general population [ 5, 6].
The wide range of prevalence rates in these studies might be related to methodological differences between the studies, discrepancies in the application of criteria in different languages, differences in sociocultural backgrounds, and genetic factors.
Two investigators independently identified eligible studies; discrepancies were resolved by consensus with a third investigator.
For the quality assessment JvH & HvdH independently scored the included studies, discrepancies were examined by TVV after which consensus was reached.
During completion of the risk-of-bias assessment for the full set of studies, discrepancies between the reviewers are resolved by reaching agreement through discussion.
In most of these comparison studies, discrepancies found between the different assays were partly explained by the fact that these molecular assays were using different capture technologies for CTC isolation and very different detection systems.
Prior to the full text review, a pilot assessment was undertaken by all reviewers of 4%% of included studies, discrepancies were resolved, and changes were made to the data extraction form.
Our data offer new clues for studying discrepancy in P53 cDNA and DNA sequencing analysis.
The reason for this fundamental inter-study discrepancy is unclear, but considering the number of cell lines tested methodological differences should be considered first.
The European Prospective Investigation into Cancer - Norfolk study, however, found no association for life events within the 5 years previous to study baseline [ 20], demonstrating that factors other than the type of stress also contribute to study discrepancy.
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