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The protective potential of antibodies directed to this region of HA0 has been explored in 2 studies by immunization of mice with synthetic peptides spanning the cleavage site (32, 33).
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In a Netherland study cocooning obtained by immunization of both parents was the most expensive intervention to implement but also the most effective.
Study participants were randomized by immunization schedule (3 or 5 times monthly) and Tat doses (7.5 or 30 µg) (Fig. 1 and Table 1 and Methods).
Considering the crucial biological characteristics of TgCDPK3, we firstly studied the various immune responses elicited by immunization with the DNA vaccine coding TgCDPK3 protein and evaluated its vaccinal potentiality.
This includes high population immunity demonstrated by immunization coverage estimates and supported by seroprevalence studies where available.
These conclusions were mainly drawn from studies of EAE actively induced by immunization with complete Freund's adjuvant, a harsh treatment that profoundly impacts the general immune response.
However, the very low frequency of naïve precursors to malarial antigens primed by immunization hindered studies aimed at understanding the detailed mechanisms whereby protection is induced and maintained.
α was not associated with mean room temperature or influenced by immunization This study shows that the quantification of long-range correlations using α derived from detrended fluctuation analysis is an observer-independent tool which can distinguish developmental stages of night time Trec pattern in young infants, reflective of maturation of the autonomic system.
Nevertheless, intracellular pathological tau, including tau oligomers, was cleared by immunization in many studies including ours.
In addition, earlier studies using mouse monoclonal antibodies derived by immunization with birch pollen identified this area as important for IgE binding 43.
A potential animal model for studying protection induced by immunizations with recombinant domains of PfEMP1 could be chimpanzees (Pan troglodytes), whose natural malaria parasite, Plasmodium reichenowi, is closely related to P. falciparum [13].
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