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Plots of aggregation kinetics typically give rise to a sigmoidal curve which has a lag phase before any aggregation takes place, followed by a sharp increase after nucleation and finally a plateau due to all the protein in the in vitro studies being incorporated into the aggregates (see Figure 1).
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Dr. Cowling also urged that more studies be incorporated into the final report, including work by Dr. Robert Bruck, a plant pathologist at North Carolina State University who has done extensive research on tree damage in the Appalachians and believes that air pollution is seriously affecting the forests.
Several key features observed from recent transmission electron microscopy (TEM) studies are incorporated into the model, including the sharp interface between the lithiated amorphous shell and unlithiated crystalline core, crystallographic orientation dependent Li Si reaction rate, and large-strain plasticity.
Selected non-randomised and non-controlled prospective and retrospective studies were incorporated.
To account for heterogeneity of SMDs across studies (Cochran's Q statistic P<0.1), the overall effect size (SMD) under the random effects model was reported, in which both random variations within and between different studies were incorporated [41].
Results of these studies are incorporated into this publication.
A Microsoft Power Point presentation, MNA-SF video [ 32] and case studies were incorporated into the training session.
All 18 markers were associated with RA when previously published studies were incorporated in the analysis.
(1) Population-based as well as case control studies were incorporated.
Fifty eight papers of 59 studies were finally included (table 1); eight of these studies were incorporated in the 2009 update.
Results were similar when efficacy rates and length of stay data from clinical studies were incorporated into the model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com