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Changes in plasma D/H following ingestion of water labeled with D2O have also been described in several studies at rest or exercise [e.g., reviewed in the recent report by Armstrong et al. (2010)].
For both studies at rest and with stress, patients received a low-dose (0.01 mmol/kg at 0.05 mol/L) bolus of gadolinium (Omniscan; Nycomed, Lidingö, Sweden) approximately 2 minutes before a high-dose bolus of gadolinium (0.1 mmol/kg at 0.5 mol/L).
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Studies at resting heart rate have found rather low information contents around 0.3.
The subjects were studied at rest.
The stress study was performed ≥20 minutes after the study at rest.
The subjects are studied at rest, this may underestimate the dynamic of dopamine release and it would have be more interesting to study this phenomenon during a task.
We found no difference between insulin sensitive and resistant sedentary individuals for lysine 23 acetylation, when they were studied at rest, at least 48 h after having done any voluntary exercise.
VAS pain score, considered the gold standard of pain quantification [ 32], was used to evaluate postoperative pain severity on a scale of 1 to 10 in all the included studies, both at rest and with movement.
Table 4 presents the mean values of heart rate variability, blood pressure variability, and baroreflex sensitivity measured on both study days at rest and during deep breathing.
Table 3 presents the mean values of sympathetic nerve activity as burst frequency, burst incidence and area under the burst measured on both study days at rest, during deep breathing, at the end of maximum inspiratory apnea and during late phase II of the Valsalva maneuver.
Exclusion criteria were the presence of symptomatic central nervous system lesions, a history of thrombosis, diabetes mellitus, uncontrolled hypercalcaemia, treatment with investigational drugs within 30 days before the start of study, dyspnoea at rest due to any cause, and class III or IV congestive heart failure according to the New York Heart Association.
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