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We have designed a method whereby very large SNP lists (several gigabytes in size), combining several genotyping studies at once, can be sorted and traced back to their ultimate consequence in protein structure.
At times, family members took part in several studies at once -- a violation of the rules because studies require that participants not be taking other medications, so that the data obtained relate only to the drug under study.
The clinical trials groups are going to need to organize themselves to recruit patients for multiple studies at once, so that they won't have to run through a hundred people or more just to get one who has the mutation they are testing.
Thus no healthy volunteer could be in two studies at once in trials conducted by Pfizer.
In contrast, the DGE method based on high-throughput sequencing technology in combination with NGS transcriptome information, is more suitable and affordable for tens of thousands gene expressions studies at once.
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"You must leave my bedroom or study at once without protesting when I ask you to".
We consider subregions so that we can pick up local variations in seismicity rate, and force the algorithm to find pockets of seismicity that otherwise might have been ignored if the entire area was studied at once.
That's what bothers me about watching the commentariat opine on the douche as if he's a complex social study, at once a hapless victim and a macho-caricature with no idea what to do with himself.
This setup allowed the simultaneous study of several patients; for example, all five subjects in Montpellier, Padova, and SDRI were studied at once.
However, since only selected sites can be studied at once, these methods are not truly genome-wide and can be biased to genome compartments (for example, CG-rich versus CG-poor areas).
The children were learning reading, writing and social studies all at once.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com