All of these variables have the potential to affect the results of the studies appraised.
However, there are several probable explanations to the observed deviation from findings of existing studies appraised.
We also excluded studies appraised as low to moderate quality, as defined later.
We followed systematic review methods to identify relevant studies, appraise their quality, and synthesise the results in a transparent, unbiased, and reproducible manner.
However, the evidence in this area is limited and the studies appraised each have methodological flaws that limit the strength of the conclusions that can be drawn.
The second column lists 'evidence statements' generated, with the third column summarising the number of studies appraised at each 'level of evidence' (high [H], medium [M], low [L] and very low [VL]), with the respective references in parentheses.
To overcome these deficiencies the bivariate random effects [ 18, 19] and the HSROC model [ 20] were independently proposed; but their use by research groups in the studies appraised was limited.
Three studies, appraised as providing a low level of evidence, reported no effect from exercise or nutritional interventions 191, 192 and reported significant barriers to recruiting women to participate in the intervention 193.
Embedded within in a definitive trial should be a qualitative study appraising patient's perceptions and beliefs about their foot care experiences.
Considering this, the current study appraised the MSW practices including waste generation, collection, transportation, disposal and treatment in Chandigarh.
