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The utility of time lapse microscopy to study time dependent processes such as the cell cycle and signal transduction has been apparent since the 70's[1] [3].
To study time dependent effect, cells (2×106 cells/ml) were used for studies with dengue-2 infection at multiplicity of infection (MOI) = 1.0 for 6 to 72 hours as indicated.
Furthermore, we studied time-dependent apoptotic signaling through the death receptor pathway and the mitochondrial pathway.
We next studied time-dependent effects of Sorafenib on Hepa1-6 cells using an effective dose of 10 μM.
The objective of this study was to critical review the strategy of static assessment by using an embryo monitoring system to study time-dependent variations of scoring criteria.
Domestic fowl offer a unique opportunity to study time-dependent sperm competition dynamics.
We used this as a test case to study time-dependent transcriptome responses.
A nested case control approach is a useful alternative to cohort analysis to study time-dependent exposure [ 21].
The nested case-control approach is a useful alternative for cohort analysis when studying time-dependent exposures.
However, endpoint measurements obtained from methods that pool populations of cells are not amenable to studying time-dependent processes that show cell heterogeneity.
We are currently applying this method (with good results) to study time-dependent and dose-dependent response to low-dose ionising radiation in a 3-D skin model (manuscript under preparation).
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CEO of Professional Science Editing for Scientists @ prosciediting.com