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The resounding response from those who have studied age verification technologies, and, in some cases, put them in place, has been: good luck.
The following parameters were studied: age, gender, and the cause of missions, response time, scene time, evacuation time, and total time for each mission.
Results from outcome studies may be subject to bias, depending on the setting (community versus clinic), design (retrospective versus prospective) and characteristics of the patient cohort studied (age, types of epilepsy, specific comorbidities).
As a control for the induction of RAGE we cross-linked collagen with MG, which is a well studied AGE precursor known to signal via RAGE [30], [31].
The discrepancies for these findings could be based on many variables, including the species studied, age of the animals, and the methods of detection (e.g., only in our study was real-time PCR used).
In contrast, methylglyoxal (MG), a well studied AGE precursor, has been implicated in pro-fibrotic conditions such as atherosclerosis, and modification of collagen by MG has been shown to increase fibroblast proliferation and ECM production [10], [29] [31].
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In addition, Liu et al. [113] studied age-dependent differences in the toxicokinetics of PFOS in mice.
Han et al. studied age-related anthropometric differences in Asians by analyzing MRI images of 535 knees.
We intentionally studied age-matched male female pairs from different litters.
Lipofuscin, or the "age pigment", is the prototypical and most studied age-dependent marker.
We also studied age-stratified utilization rates, indications, and characteristics of patients undergoing these procedures.
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