Sentence examples for structures of inhibitors from inspiring English sources

Optimization efforts were aided by X-ray crystal structures of inhibitors bound to IRAK4.

Crystal structures of inhibitors bound to TACE revealed monodentate coordination of the hydantoin to the zinc.

The mode of binding was explored through crystal structures of inhibitors in complex with tankyrase-2.

In addition, the fragment structures of inhibitors are combined in the similar hydrophobic pockets through the hydrophobic forces.

However, it is very risky to explore new structures of inhibitors.

The structures of inhibitors are rather different representing different classes of chemical compounds, and there are no metal atoms nearby the active site.

These problems hampered the structural modifications of H3H guided by insights from computer simulations or the crystal structures of inhibitor-bound BoNTAe complexes.

Many structures of inhibitor complexes of vacuolar plasmepsins, as well as their zymogens, have been reported in the last 15 years.

The crystal structures of inhibitor complexes of caspases-3 and -8 validate the design of the inhibitors by illustrating in detail how they mimic peptide substrates.

In this study, we used solved x-ray structures of inhibitor-bound PDEδ targets to investigate mechanisms of action of six independent all-atom MD simulations.

Here, we report the X-ray crystal structures of inhibitor-bound inactive and active TBK1 determined to 2.6 Å and 4.0 Å resolution, respectively.