The mesenchyme of kidney tubule showed massive fibrosis, thus the three-layer structure of filtration membrane was undistinguishable.
The objective of this study was thus to apply, for the first time, an optical method for in-situ, non-invasive, characterization of cake structure during filtration of a real biofluid in presence of particles.
NEPH-1 is involved in maintaining the structure of the filtration barrier and also interacts with nephrin [ 75].
The ultrastructure alternations of renal cells as we found in ET rats were pronounced e.g. disorganized three layers structure of glomerular filtration membrane, mesenchyme fibrosis and cell apoptosis, etc.
The final step of structure filtration is the check of the proximity of the calculated and experimental spectra for each structure.
To date, no studies have clearly dissociated the impact of these two phenomena as a method was needed for the in-line characterization of the cake structure during filtration.
What is necessary to raise the patients' quality of life is an improvement of the filtration structure of membranes and the refinement of filtration parameters.
The membrane stability was also investigated in terms of the persistence of nanoparticles inside the membrane structure during filtration process.
The influence of filtration flux and membrane structure are studied.
The spectral filtration of structures proceeds simultaneously with generation, and three modes of filtration severity can be specified taking into account the ambiguity of boundaries of characteristic spectral ranges.
If we evaluate the results of filtration by means of the tested ANFIS structures, it is clear that all the structures achieved a significant improvement in the SSNR values.
