Sentence examples for structures of acridones from inspiring English sources
Figure 1 Structures of acridones 1- 10.
The 3, 4-cyclization is normally preferred for a more stable linear structure of acridones.
By combining the structural features of acridone based anti-cancer drugs (like amsacrine) and MDR modulator propafenone, acridones with hydroxyl amine chain at N-10 have been designed and synthesized.
In summary, a nitric oxide donating group can potentiate the anti-MDR property of acridones.
The ability of acridones to inhibit calmodulin dependent cAMP phosphodiesterase has been determined.
In the present study, we aimed to elucidate the chemosensitization potential of acridones by employing various molecular modelling techniques.
Hybrid systems of acridones with substituted pyrimidines were designed with an objective of discovering next generation anticancer agents targeting multiple mechanisms in the cancer cell.
On the basis of the chemical structures of psorospermin with a xanthone template and acronycine derivatives with an acridone template, rac-1 and rac-2 constructed on an 1,2-dihydrobenzofuro[4,5-b][1,8]naphthyridin-6(11H -one scaffold were designed and synthesized as potential anticancer agents.
He thus recognized structures of imperial origin.
The structures of the new compounds were elucidated mainly by UV, IR, NMR and MS spectroscopy (Additional file 1) and by comparison with the data already reported in the literature for acridone alkaloids [5, 25 32].
Examination of the relationship between lipophilicity and cytotoxic properties of acridone derivatives showed a poor correlation.
