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Thus, on balance, it does not seem likely that riboprobe affinity to structured versus unstructured transcripts explains the observed enrichment of structured transcripts.
The processing patterns of hairpin structured transcripts derived from relevant vectors could be different.
However, this result does not exclude that DRB2 can bind other type of long structured transcripts in vivo.
In the absence of tdp-1, potentially structured transcripts are both increased and decreased in the mature (poly-A) RNA pool.
The significantly enriched expression energy of structured transcripts is hard to explain by chance and supports the theme of functional RNA structures in the mouse brain.
RNA editing was previously hypothesized to mark aberrant and/or structured transcripts for retention in the nuclear compartment via a p54nrb-dependent mechanism [ 38- 40].
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For each PSG gene, there are annotated RefSeq resources comprising information on genomic structure, transcripts and translation products.
To obtain the RNA secondary structure, transcripts were incubated at 70°C for 15 min and cooled down at room temperature for 20 min.
Information about the gene structures, transcripts, full-length cDNA, BAC accessions for each gene and characteristics of corresponding proteins were procured from MSU RGAP and KOME http://cdna01.dna.affrc.go.jp/cDNA/.jp/cDNA/
This catalog reveals that several regulatory processes are engaged by Mn deficiency, including changes in chromatin structure, transcription, transcript maturation and stability, as well as alterations in translation efficiency and protein stability.
This process may include many levels, such as chromatin structure, transcription, transcript stability or localization, and translation.
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