Sentence examples for structured probes from inspiring English sources

We have designed an electrochemical DNA biosensor based on stem loop structured probes for enzymatic detection of Pseudomonas aeruginosa 16S ribosomal RNA (rRNA) in composting degradation.

The stem loop structured probes were "closed" when target was absent, then the hybridization of the target induced the conformational changes to "open", along with the biotin at its 3′ end binding with streptavidin-horseradish peroxidase (HRP), and subsequent quantification of the target was detected via electrochemical detecting the enzymatic product in the presence of substrate.

We subdivided structured probes into two genomic locations: (1) structured (long) noncoding RNAs (ncRNAs) have no protein coding potential and the entire probe is intergenic or intronic, and (2) structured UTRs are probes overlapping a UTR exon annotated in UCSC or RefSeq gene tracks with an RNA structure prediction.

By comprehensive spatial expression analysis of the adult mouse in situ hybridization data of the Allen Mouse Brain Atlas, we show that transcripts (coding as well as non-coding) associated with in silico predicted structured probes are highly and significantly enriched in almost all analyzed brain regions.

The draft questionnaire was administered using concurrent cognitive probing, in which respondents answered the tested questions as the interviewer read them, and interviewers also administered structured probes that assessed how respondents interpreted key questions or phrases and how they selected questionnaire responses.

Our main concern is whether "structured probes", i.e., those containing a conserved RNA secondary structure as predicted by, are in any other way a distinct population compared to "unstructured probes", i.e., those lacking such predictions.

For non-structured UTR probes there are four times less enriched GO terms, in general with lower significance than for structured UTR probes.

We found support for function enrichment of binding (p=5E-40), localization (p=4E-18) and transport (p=4E-16) in structured UTR probes.

DNA hairpin structure probes are usually designed by forming intra-molecular duplex based on Watson Crick hydrogen bonds.

In these cases, the electron paramagnetic resonance (EPR) is more effective, especially, when paramagnetic centers with high spin serve as structure probes.

RNA structure probes are a class of molecules that take advantage of RNA reactivity.