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At first, predicted secondary structure sequences are mapped into two time series by the chaos game representation.
In combination with other 11 rational features based on predicted protein secondary structure sequences proposed by the previous researchers, a 36-dimensional representation feature vector is presented to predict protein secondary structural classes for low-similarity sequences.
Among the 111 features, 100 features based on pseudo-position specific scoring matrix (PsePSSM) are selected to reflect the evolutionary information and the sequence-order information, and the other 11 rational features based on predicted protein secondary structure sequences (PSSS) are designed in the previous works.
By combining information derived from the low-resolution x-ray structure of the 70S ribosome (providing the overall fold), high-resolution structures of the ribosomal subunits (providing the local structure), sequences, and secondary structures, we have developed an atomic model of the T. thermophilus ribosome using a homology modeling approach.
Using mouse miR-433 and miR-127 precursor hairpin structure sequences as a query, we searched the genome databases of seven other species, including human, chimpanzee, horse, dog, monkey, rat, and cow.
All the RNA samples used in our expression study had RIN values between 7 and 9. 1 microgram of RNA (excluding small RNAs) from each of the 28 subjects (17 PDs and 11 controls) was labeled for hybridization to Affymetrix Human Exon Arrays covering known cDNAs, ESTs, and predicted gene structure sequences, using standard Affymetrix protocols.
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Some software authors in the 1980's tried to extend their copyright protection beyond the literal code, to elements at higher levels of abstraction: a common phrase was "structure, sequence and organization".
Such efforts further our capacity to control, design and understand biomolecular structure, sequence and function.
In this paper, features based on the predicted secondary structure sequence and the corresponding E H sequence are extracted.
Computational protein design facilitates the continued development of methods for the design of biomolecular structure, sequence and function.
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence).
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