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In addition, the process of conceptual redesign is analysed in detail, such as the process of function feature planning based on QFD, structure redesign, and so on.
These latter efforts represent one of few examples of productive core structure redesign of a natural product.
Significantly and unlike modifications of peripheral substituents (tailoring effects), core structure redesign in such complex natural products is rarely explored, and the results in this series indicate this may offer far more opportunities than most might anticipate.
We use the HCS to analyze MD duty schedules before and after the implementation of a schedule structure redesign intended to maximize patient and MD familiarity and continuity within the context of defined scheduling constraints.
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In most cases, the owner-manager is not prepared or does not wish to have the organizational structure redesigned.
To compete in the big emerging markets, multinationals must reconfigure their resources, rethink their cost structures, redesign their product development processes, and challenge their assumptions about who their top-level managers should be.
Embedded within the organizational context of the project- based organization (PBO) that possesses them, their development often requires reconfiguring structures, redesigning processes and even renegotiating organizational norms.
The team then used their cryo-EM structure to redesign mefloquine so that it bound more strongly to the ribosome, making a derivative that was twice as effective at killing the parasite.
While the obvious example is Penn State, a review of salary structure, facilities redesign and new construction and administrative bloat raises serious questions about the use of fund-raising time and bond capacity to support athletics.
Szczepek, M. et al. Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases.
The concurrent structure-control redesign approach is stated as a dynamic optimization problem (DOP).
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