Your English writing platform
Discover LudwigExact(5)
The solution structures are similar to the crystal structure of the cyclic inhibitor in complex with trypsin.
Using computer assisted molecular modeling, a putative pharmacophore was constructed from the superposition of the reported three-dimensional structure of the cyclic peptide BQ-123 and a presumable β-turn active conformation of the linear peptide FR139317 formed by an intramolecular hydrogen bond.
The refined structure of the cyclic hemiacetal 10 was then converted to the corresponding aldehyde 7, which represented the reactive species necessary for DNA cross-link formation.
The refined structure of the cyclic hemiacetal 8 was then converted to the corresponding aldehyde 6 that represents the reactive species necessary for DNA cross-link formation.
It is therefore interesting to compare the structure of the cyclic mononucleotide-binding domain of CRP with cyclic AMP bound with that of XC_0249 with cyclic GMP bound that we describe here.
Similar(55)
A strong correlation between the structures of the cyclic voltammograms and the potential dependence of the Warburg diffusion impedance is observed, which is determined by the concentrations of the redox species under consideration.
The structure of the resultant cyclic derivative was confirmed by means of NMR and X-ray crystallography.
2– 4 Herein we report the synthesis and structure of the stable cyclic phosphanylidene-σ-phosphorane 3 (see Scheme 1).
When the cyclicon hybridizes to the complementary target nucleic acid strand, the intramolecular cyclic structure of the cyclicon is destabilized and opened up, separating the fluorophore and quencher groups, resulting in spontaneous fluorescence emission.
The structure and compositions of the cyclic trimers were confirmed by 1H and 29Si n.m.r.
It was important to analyse the structure of the newly designed cyclic TSP-1 analogues to determine whether these peptides adopt similar conformations to their native frameworks.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com