Sentence examples for structure of copy from inspiring English sources

Few of the existing methods (reviewed below) provide an explicit description of the null hypothesis being tested, or fully acknowledge the inherent correlation structure of copy number data.

Cancer cases were divided into separate clusters for each chromosome using the inherent structure of DNA copy number amplification models.

Comparison between genomic copy number (as identified by CGH) and gene expression (as measured by arrays) is complicated by the fact that CGH does not resolve the fine structure of genome copy number changes.

The biological motivation for cyclic shifts is clear for organisms such as bacteria that have circular chromosomes, for the serial structure of the copy number data from a given row is completely preserved under cyclic shifts.

Overall structure of actively copying Pol α. (A ) The polymerase domain of yeast Pol α is shown in complex with an RNA primer/DNA template and dGTP bound in the active site.

It has been argued that the evolution of novel functions in a new gene duplicate may be facilitated by radical changes in the exon-intron structure of the derived copy, typically manifest in structurally heterogeneous paralogs comprising partial and chimeric duplicates [ 3].

Some version of this structure or copy of it is or was present among all these groups.

The gene structure of each EPSPS copy was originally predicted using NetGene2 and Neutral Network splice-junction analysis programs [ 33, 34], and then confirmed by comparing genomic and cDNA sequences (Fig.  2).

Is the evolution of novel function primarily facilitated by changes to the intron-exon structure of the derived copy relative to its progenitor as manifest in partial and chimeric duplicates or do regulatory changes (rapid promoter evolution or the gain of novel promoters) play a significant role?

As a first step towards a detailed examination of the structure of the retrotransposed copies of the tagged Zorro3 elements, the 3' ends of 30 independent copies were amplified by inverse PCR and sequenced (Table 1).

The results indicated that all signals are located in the long arm of X chromosome (see additional file 4), suggesting that all the copies are possibly tandem duplications on Xq24, which was partially reflected by the determined genomic structure of the three copies in chimpanzees (figure 1b).