Exact(26)
System identification involves determination of the functional structure of a target system that underlies the observed data.
One of the challenges for researchers is to guide the action of catalysts in a way that alters the molecular structure of a target, like a natural product, to eliminate toxic effects while retaining beneficial properties.
Elemental MS, such as inductively coupled plasma mass spectrometry (ICP-MS) can overcome these drawbacks; in fact, analytical performance is theoretically independent of the molecular structure of a target analyte naturally containing the elements of interest.
A key technique is the use of methods including X-ray crystallography and NMR for the determination of the 3-dimensional structure of a target protein followed by various modelling techniques for the design of small molecule ligands that could interact with the target structure.
The monomeric structure is inferred by mapping given monomers to the atomic structure of a target polymer.
Completely different is the approach used by Snowball Samples or Respondent Driven Sampling (RDS), which rely on the network structure of a target population.
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The method modifies the structure of a target-near-surface by bombardment by ions [11].
The Shaker protocol (Additional file 2: Table S9) was formulated during multiple trials (Additional file 2: Tables S5 and S6) and results in a final solution structure of a target-ligandn complex, where n is the total number of final cluster representatives.
Another common task in cheminformatics is the selection of a set of molecules of similar structure to a target molecule.
Therefore, the predicted secondary structures of a target exon were not sensitive to sequence length of the window of analysis.
It was demonstrated that the validity of multiple templates-based modeling mainly relies on the primary structure identities of a target protein with template ones, and on the multiple alignment accuracy among crystal structures of templates (Madhusudhan et al. 2009).
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