Sentence examples for structure of a dna from inspiring English sources
Structural studies of UL30 showed that it forms the typical hand-shaped structure of a DNA polymerase with the catalytically important residues for dNTP polymerization in the palm domain.
The concept, which he called antisense technology, is based on the double-stranded structure of a DNA molecule.
However, it is a truism that whenever a mutation regime shapes the primary structure of a DNA sequence for a long time –and the results in the previous pages leave little doubt about this being the case for NBDM in vertebrates– then a different mutation regime is likely to generate more mutations on such DNA than the actual regime which structured the DNA over the long term.
Epigenetic alterations in gene expression may be achieved through changes in the tertiary structure of a DNA strand.
The structure of a DNA molecule is primarily determined by its nucleotide sequence, so that similar DNA sequences have similar DNA structures.
Fernandez-Leiro, Conrad et al. have now used a technique called cryo-electron microscopy to reveal the three-dimensional structure of a DNA polymerase from a bacterium called Escherichia coli complete with other associated factors and a DNA molecule.
The intercalated dinucleotide step is strongly perturbed, with a twist of nearly 10° and a rise of 7.3 Å (36° and 3.4 Å for a canonical B-helix, 33° and 2.7 Å for A-DNA), typical of an intercalation mechanism (as observed, for example, in the structure of a DNA-nogalamycin complex [39]).
When the number of pools is J ≥ 2, the structure of a pooled DNA study is an example of a two-stage nested design [ 18].
In general, the C-terminus amino acid sequence is rich in basic amino acid residues, such as arginine and lysine, and resembles the structure of a mammalian DNA binding protein, protamine [ 16, 17].
We report here the crystal structure of an SF3 DNA helicase, Rep40, from adeno-associated virus 2 (AAV2).
Their structure is thought to mimic the structure of an open DNA promoter [ 88, 89].
