Sentence examples for structure backbone from inspiring English sources

Exact(9)

Based on the molecular docking analysis compound 3g optimization work was performed, and then a new structure backbone of N-nitrourea compound was designed for further research.

A single nanopore represents a versatile single-molecule probe that can be employed to reveal several important features of proteins, such as physical structure, backbone flexibility, mechanical stability, their folding state, binding affinity to other interacting ligands and enzymatic activity.

Collectively, the data make a convincing argument that single and site-specific tethering has little effect on secondary or tertiary structure, backbone dynamics, or conformational equilibria.

Many questions remain open, such as the role of chain flexibility, molecular structure (backbone and side-chain lengths, chemical composition of the side chains, etc)., and the exact organization of the polymers at the interface in the film.

The main conclusion of general interest is that the tertiary structure, backbone dynamics, and conformational equilibria of T4L derivatives attached site-selectively to a Sepharose matrix are unperturbed relative to the protein in solution for the sites investigated.

In conclusion, the challenge for future studies will be to improve both the AON structure (backbone) and molecule protection by NPs to improve the AON bioavailability and to enhance the intestinal cells' uptake of orally delivered drugs.

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Similar(51)

We have presented a method for instantiating full atomic detail in coarse-grain RNA structure backbones using geometry knowledge from a reference database of one or more full atomic RNA crystal structures, in this case the Thermus thermophilus 16S ribosome.

In the EE-case the use of confidence levels by means of an online questionnaire initially formed the structuring backbone of the approach.

The structures determined by PONDEROSA were very similar to those determined earlier by more manual approaches: 1.15 Å RMSD for the backbone atoms of human ubiquitin (PONDEROSA versus 1D3Z) and 1.30 Å for structured backbone atoms IscU D39A) (PONDEROSA versus 2KQK) (Supplementary Fig. S1D).

In this Feature Article, we focus on how the orientation of semiconducting polymer backbones are influenced by the chemical structure, e.g., backbone structure, molecular weight, and side chains, and processing conditions.

They add cabernet to merlot "to give it structure, or backbone".

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