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In addition, this new experimental approach allowed the assignment of functional epitopes of structurally specific ligands used for selection [Fc γ‐receptor I (CD64) and anti-human CH2 domain antibody] to distinct binding regions in the CH2 domain.
A randomly mutated library of the crystallizable fragment of human immunoglobulin G class 1 (IgG1-Fc) was expressed on the surface of yeast, followed by heat incubation at 79 °C and selection of stable variants that still bound to structurally specific ligands.
However, a detailed kinetic study demonstrates that the employ of bimetallic Janus Au-Ni NPs in the NCs indicates enhanced catalytic activity, owing to the structurally specific nature.
This suggests that the peptide's cellular target(s) may also be structurally specific.
Only stabilized scTCR and MHC variants resisted thermal unfolding and still bound to a structurally specific ligand after the heat shock.
This role is exclusive to ascorbate, which is structurally specific for the hydroxylase active site 13, 15, and the role cannot be fulfilled by other antioxidant molecules 16.
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Das, R. et al. Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding regiof of gp78.
The method is based on incorporation of structurally non‐perturbing, specific binding motifs for a bis‐arsenical fluoroscein dye, FlAsH, in sites that result in distinct dye fluorescence signals for the folded and unfolded states of the protein under study.
Structural DNA nanotechnology consists of combining unusual DNA motifs by specific structurally well-defined cohesive interactions (primarily sticky ends) to produce target materials with predictable 3D structures.
Modern penicillins are semisynthetic compounds, obtained initially from fermentation cultures, but then structurally altered for specific desirable properties.
In addition, calcium-phosphate materials can be technologically modified, chemically and structurally designed with specific architecture, forms, and geometry [16].
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