Exact(3)
Therefore, the present study was designed to test the potential inhibitory effect of tree structurally relative sesquiterpenes β-caryophyllene (CAR), β-caryophyllene oxide (CAO) and α-humulene (HUM) on the activities of the main drug-metabolizing enzymes.
One hypothesis is that the products of the novel reductase genes (NPH_5472-76) reduce the first ring of the double naphthalene ring (since it is most unique structurally, relative to benzoate) and then the products of bcr-like genes (NcrABCD) reduce the second ring in manner analogous to benzoate degradation.
How has influenza C changed structurally relative to types A and B? Can one recognize, in type C, greater selective pressure for reproductive rate compared with mutability when contrasted with types A and B? We seek conditions under which an antigenic variant remains the dominant type in the pathogen population.
Similar(57)
As a result, the curve must be structurally steep relative to historical experience when the Fed had room to cut.
Following assembly, zebrafish NODs were highly structurally conserved relative to human NODs.
The latter possibility might open the way to structurally unknown relatives of the largest known fullerenes.
The structure determined here is also essentially identical to the structure of a smaller BARD1 BRCT fragment recently determined by Birrane et al. The N-terminal domains of BRCT repeats whose structures are known are structurally well conserved relative to their C-terminal BRCT domains, which tend to have larger and more diverse loops.
Specific examples where this approach has generated either significant modifications of existing molecular frameworks or structurally new molecular templates relative to design starting points (i.e., lead hopping) will be provided.
The high selectivity for BPA relative to structurally related guest molecules was estimated to be 1.6 3.4 at the guest concentration of 2 × 10−7 M, and was considered to arise from the synergic effect of the binding site.
To identify candidate miRNAs we relied on genome-wide miRNA profiling of PGLs relative to structurally normal JN, the tissue of origin of tympanic PGL [ 32].
Full-thickness articular cartilage lesions that reach to the subchondral bone yet are restricted to the chondral compartment usually fill with a fibrocartilage-like repair tissue which is structurally and biomechanically compromised relative to normal articular cartilage.
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