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All eight inhibitors structurally examined occupy the binding site of α-ketoglutarate, but differ in their specific binding interactions, including the number of ligands involved in metal coordination.
Two new supramolecular zinc frameworks, [Zn 2-MeBIM 2 OAc 2]·3H2O (1) and [[Zn 2-MeBIM)(Pht)(H2O)]·2H2O]n (2) (where 2-MeBIM = 2-methyl benzimidazole, OAc = acetate anion and Pht = dianion of phthalate), were crystallized, and structurally examined.
To date, only two substitutions (K48A, R42P) have been structurally examined in the Ubl domain leaving the majority of the disease-related substitutions uncharacterized.
The majority of studies on REMPs focus on members identified from the model organism E. coli, however, REMPs from other Bacterial and Archaeal species have been functionally and structurally examined (as reviewed by [ 9, 10]).
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In-gel probing may therefore be a more accurate way to structurally examine RNAs that form only one native, physiologically relevant structure, as well as to examine structural switches.
We used well-structured classic method, the principal components analysis (PCA) and Rasch analysis for structurally examining the 13-item FACIT-F.
Then, using dark-field imaging, we structurally examine the reaction intermediates with 1 nm resolution.
This project identifies how instructors and departments adapt SCALE-UP, pedagogically and structurally, and examine how that relates to adoption, implementation, and sustainability.
For each reaction, four reaction pathways were examined structurally and energetically.
These mutants were tested for their ability to cleave and to catalyze asparagine hydrolysis, in addition to being examined structurally.
The powders and gel electrolytes have been examined structurally and electrochemically, showing favorable properties in terms of electrolyte uptake and electrochemical characteristics in Li-ion cells.
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