Sentence examples for structurally critical from inspiring English sources

Comparison of the amino acid sequences with the 3-dimensional structures of these LPBP-B proteins revealed several conserved amino acids in structurally critical elements of the polypeptide fold (Additional file 2).

Tishman Construction is the construction manager. 2 AND 3 WORLD TRADE CENTER The foundations of these two skyscrapers, to be developed by Silverstein Properties, flank — and are structurally critical to — the Transportation Hub.

It has been also reported that there are several structurally critical points on the embankment that are potential for breaching in the near future as of 2008 event (Sinha and Kommula 2010).

Residues which are known not to be structurally critical and/or subjected to change during the in vivo maturation process were identified in the MLG analysis and humanized.

Failure of CTL responses to strongly target functional or structurally critical regions of the virus, as well as the sequential cascade of CTL responses, followed closely by viral escape and decline of the corresponding responses, likely contribute to a lack of sustainable viral suppression.

Instead, they were at the structurally critical points, such as the membrane spanning region or inside the pore regions in the present study.

This supports the notion that the conservation/divergence in surfaces of different ferritin paralogues occurred amongst structurally-functionally critical residues that form these surfaces at the same rate presumably dictated by the need of the organism to perform different functions.

D3 receptor ligands contain a positively charged group, usually a protonatable tertiary amine, which forms a structurally and pharmacologically critical salt bridge to the carboxylate of Asp1103.32 as found by site-directed mutagenesis [13] and confirmed by the crystal structure [14].

Purifying selection is expected to be higher at structurally and functionally critical positions, such as protein-protein binding surfaces.

These annotations predict the position of structurally and/or functionally critical sites and thus are expected to be evolutionary constrained.

Every day, U.S. commuters are taking more than 200 million trips across deficient bridges, according to a variety of analyses, and at least 8,000 bridges across the country are both "structurally deficient" and "fracture critical" — engineering terms for bridges that could fail if even a single component breaks.