The resulting structure-based alignment depicts structurally analogous residues, not homology.
As a consequence, this hierarchical two-step fragmentation scheme identifies all compound subsets that have structurally analogous cores, i.e., core structures that are only distinguished by a structural modification at a single site.
Notably, in a survey of the Cambridge Structural Database (CSD) (version 5.34, update 3, November 2012) of structurally analogous triazoles, we determined 6 of 32 molecules to exhibit noncentrosymmetric packing based on hh stacking geometries.
The 2D structural features were active in most components, identifying similarities in structurally analogous drugs.
In this respect, young trees are structurally analogous to the herbaceous plants.
The vertebral column and associated muscles of many mammals are structurally analogous to a cantilever girder.
Phosphorus molecules of formula P2, structurally analogous to N2 molecules and evidently also triply bonded, exist only at very high temperatures.
But Ms. Pike, whose presence at first seems structurally analogous to Emma Watson's role in "This Is the End" — that is, the token woman in a naughty man-child comedy — deserves commendation for her quick wit and robot-fighting skills.
One might, therefore, expect that BN substituted C60 fullerenes are structurally analogous to pure C60.
Eight novel polymerizable monovalent quaternary ammonium bromide surfactants and five model non-polymerizable structurally analogous surfactants have been synthesized.
As SSR504734 is a structurally analogous compound to [11 C]N-methyl-SSR504734, the possibility of interaction at a nonspecific binding site was not completely excluded.
