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The heterogeneity of mhttQ51 fibrils precluded us from resolving their structure in detail since all current structural techniques require some underlying homogeneity in fibrillar structures to achieve high resolution.
Therefore, in general, folding algorithms are used for the prediction of the structure corresponding to the consensus sequence, whereas experimental structural techniques can be applied to the determination of the structure corresponding to the most abundant sequence in the population.
Over the past 15 years, the power of molecular and structural techniques has revolutionalized our understanding of the biogenesis, structure, function and mode of action of these bacterial organelles.
The fine structures of the PLLA-TC film were studied by various structural techniques such as X-ray diffractometry, optical microscopy and transmission electron microscopy.
As well as demonstrating the power of combining multiple high resolution structural techniques, this new needle model has implications for the structures of the periplasmic rod and distal tip assemblies.
In summary, our structural model identifies many of the dynamic subunits, not revealed by other structural techniques, that provide an important additional layer of complexity to the quaternary structure of human U1 snRNP.
Prouvé pioneered new structural techniques that would permit the efficient and inexpensive construction of buildings with prefabricated components while retaining architectural quality and individuality.
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For small helical membrane proteins, their structures are highly sensitive to their environment, and solid state NMR is a structural technique that can characterize these membrane proteins in native-like lipid bilayers and proteoliposomes.
His first major building was a polite neo-classical headquarters for Woolworth's on Marylebone Road in 1956, but four years later his style and structural technique had changed radically, like Bob Dylan going electric.
Machaut also continued the composition of motets, organizing them around recurrent rhythmic patterns (isorhythm), a major structural technique of the age.
Zhan and Clark [46, 48] describe an alternative for the test data generation using the structural technique.
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