Sentence examples for structural nucleus from inspiring English sources

Numerical modelling studies of the kinetics of fibril formation at different protein concentrations, which included over 20 different possible assembly mechanisms, suggest that the initial molecular recognition events involve the assembly of monomers leading to the formation of a high-energy structural nucleus consisting of six β2m polypeptide chains.

Recent work from Day and Daggett showed that folding/unfolding from a structural nucleus obeys the principle of microscopic reversibility to a large extent, when performing simulations close to the melting temperature of the protein where folded and unfolded states are equally populated.

The destruction of the lamin networks is controlled by specialized apoptotic proteases called caspases, which cleave the lamin proteins and, thus, degrade the nucleus' structural integrity.

This is achieved by a biomechanical balance between the IVD's two main structural elements, the nucleus pulposus (NP) and the annulus fibrosus (AF).

In this study, we estimated acetylation stoichiometry on a known regulatory site in the nucleus, structural maintenance of chromosomes protein 3 (SMC3) K106, which was 4% acetylated (Rolef Ben-Shahar et al, 2008; Zhang et al, 2008).

During interphase it plays a crucial role in structural organization of nuclei, transcription and splicing of ribosomal RNA.

Our longterm goal is a search for structural features of nuclei, which are restricted to certain cell types/species, as compared to features, which are evolutionary highly conserved, arguing for their basic functional roles in nuclear organization.

We propose that the BRG1-dependent nuclear shape changes reflect a role for the chromatin remodeling enzyme in maintaining the structural integrity of the nucleus via global regulation of chromatin structure and dynamics within the nucleus.

Blobel also studied lamins, which are proteins involved in providing structural support to the nucleus.

Mice lacking critical structural components of the nucleus, lamin-B intermediate filament proteins, remain viable until birth.

Accurate measurements of nuclear deformation, i.e., structural changes of the nucleus in response to environmental stimuli, are important for signal transduction studies.