Sentence examples for structural mutants from inspiring English sources

Identification of all structural mutants of lipid A is critical because different structures modulate the immune response to varying degrees.

Similarly, the slow-growth phenotype conferred by CTK2 deletion is not altered by the U2 structural mutants (Figure 2C).

To examine the protein product of the EGFP-Mena structural mutants, we performed western blot analysis of whole-larva extracts of each how 24B-Gal4:UAS-EGFP-Mena transgene.

Currently, specific transcriptional programs or cell phenotypes cannot be correlated with selected missense p53 mutations or even with the broad distinction between contact and structural mutants (39) (Table 1).

Compounds aiding the refolding of structural mutants into a wild-type conformation may still not be active because they do not trigger the post-translational modifications that are necessary to obtain a p53 response.

The interaction between sugar signaling and cell wall integrity control was also highlighted by the sugar hypersensitivity of several cell wall matrix structural mutants mur4, mur1 and mur3 [ 9].

For the FIV Rev, we obtained a significant threading score for the region corresponding to amino acids 16 145 against the structure of interleukin 4 structural mutant [38].

The comparison of the level and kinetics of A9-N1 methylandotherd other secondary modifications in the unmodified, misfolded mt-tRNALys and in a cloverleaf-shaped structural mutant, engineered to adopt the tRNALys cloverleaf structure without post-transcriptional modifications, suggested strongly that the methylation of A9-N1 in tRNALys proceeds via a cloverleaf-shaped intermediate.

To ascertain the physiological effects of p53 point mutation, the structural mutant p53R172H and the contact mutant p53R270H (codons 175 and 273 in humans) were engineered into the endogenous p53 locus in mice.

Mena structural mutant vectors were a gift from F. Gertler (Loureiro et al., 2002).

Group 1 (MBL-low) consisted of patients with two structural mutant alleles (0/0) or on one haplotype a structural mutant allele together with another haplotype containing an LX promoter and the wild-type structural allele (ALX/0).