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While structural methods have enjoyed great success in determining structures of isolated rhodopsins and their binding partners, structures of inactive and activated protein complexes, especially those of membrane and soluble proteins, remain elusive.
An alternative approach using structural methods is to determine whether there are any structures that have a primary sequence similar to putative homologs.
In this approach, mathematical models play a central role for the evaluation of the alternative network structures that arise from literature data-mining, phylogenetic profiling, structural methods, and human curation.
Drawing a parallel, here we demonstrate that LDA indeed models relationships between fragments in protein structures effectively and achieves a competitive performance with state-of-the-art structural methods at a fraction of the computation costs.
i use both reduced form and structural methods.
With the advances of 20th-century technology, new structural methods such as cantilevering received more extensive use.
This affected the design of masonry architecture by transforming its proportions and decoration and even its structural methods.
Structural methods have remained largely unexplored in this regard.
Yet the tension between these various styles was paired with a desire to innovate with new materials and structural methods.
It is she who comes up with the images that seem to sum up Mr. Pinter's own structural methods: a car traveling fast in reverse, for example, or her drawing a figure in the sand.
Structural methods based on efficient graph theoretical algorithms are used in several steps.
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