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Superposition of the two structures reveals major structural dissimilarities between the two paralogs at the CRY secondary pocket and a residual fusion-protein sequence (yellow) in CRY1-bound PER2-CBD.
The structural dissimilarities (substitutions and additions marked in red) of five familiar compounds relative to oxaloacetic acid are highlighted to provide context to the calculated similarity score.
Second, structural dissimilarities between small equivalent swapped domains can blur the boundary of hinge loops.
Our sequence analyses and molecular modelling of H. pylori and E. coli ICDs did not reveal complete structural overlaps between the two (Figure 1); several regions of structural dissimilarities were discerned which possibly correspond to the putative antigenic epitopes in H. pylori ICD.
The identified non-conserved regions and structural dissimilarities of Rab7/Rab9 proteins may be a good starting point to further functional and structural studies.
Structural dissimilarities between bisphenol AF and BPA are determined by the presence of a trifluoromethyl (CF3) or methyl (CH3) group, respectively.
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In agreement, the greatest structural dissimilarity between Rab7 and Rab9 structures was just found in active switch conformations [ 126].
The 3-D superimposition of protein structures obtained by using structure comparison tools is very useful in quantifying structural dissimilarity and in analyzing structural divergence.
The results were then compared to those of linear analogous poly ether ketone) (LPEK), which was prepared to investigate any difference in these two characteristics due to their structural dissimilarity.
Figure 10 Structural dissimilarity map of the first two frames of the continuous-tone caltrain sequence.
To examine this structural dissimilarity, we built a similarity matrix based on compounds' MACCS keys and using abacavir as the active reference probe (Table 1).
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CEO of Professional Science Editing for Scientists @ prosciediting.com