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Scanning electron micrographs illustrated the severely structural disruptions of sample cells by PSE.
The exact causative factors have not been clearly defined, and development may result from structural disruptions in the connective tissue of the fasciae.
Furthermore, proline mutagenesis revealed that the mechanical design of TNfn3 is robust and the mechanical stability of TNfn3 is very resistant to structural disruptions caused by proline substitutions in β sheets.
Taken together, these data suggest that structural disruptions of the fornix and cingulum bundles may occur in schizophrenia.
Signature I of L. panamensis SIDER2 at insertions 1 and 2 had severe structural disruptions (Additional file 1: Figure S1).
Secondary dRTA occurs in a great number of circumstances related to autoimmune diseases, drugs and toxins, and genetic or structural disruptions of renal tubules.
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RNAmutants samples mutant sequences and structures according to their probability in the structural ensemble to identify sequences that severely disrupt structure, but fundamentally determines the structural disruption based on the MFE structure of the mutant [ 36].
However, prolines display important differences with the other amino acids because they cause a characteristic structural disruption of secondary structures, and it has been suggested that the abundance of non-contiguous prolines decrease the prionogenicity of a given sequence [ 30].
Since this could indicate either loss of CGRP affinity, absence of receptor expression or severe indirect structural disruption of the receptor structure, these mutants were not analysed further in this study.
Since the algorithm relies on predicted structural disruption, it works especially well where protein structure is known and less reliable when a solved protein structure is not available.
The semantic and structural disruption, starting with the novel's unfinished title, reflects its anarchic intent – to disrupt the comfortably smug, middle-class sensibility personified by Genevieve and her dinner party set, with their stultifying prejudice and snobbery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com