Sentence examples for structural denaturation from inspiring English sources

The higher storage stability of the PHS nanogel could be explained as the prevention of structural denaturation as a result of the encapsulation of PHS by polyacrylamide [44].

However, freezing may cause structural denaturation in enzyme solutions and loss of biological functions due to pH variations and "stress" (aggregation, unfolding, and dissociation) caused by the formation of ice crystals and freeze thaw cycles, which reduce enzyme stability.

However, the enzyme activity was improved at pH 4.0 and above 8.0 and the stability of the immobilized enzyme was highly improved at pH 5.0 and 6.0, suggesting that the alginate matrix protects the enzyme from structural denaturation by changes in pH (Keerti et al. 2014; Su et al. 2010).

This phenomenon may be due to the reduction of water activity around the protein molecules promoting structural denaturation [ 1, 8].

By a combination of two magnetic resonance methods, electron paramagnetic resonance and nuclear magnetic resonance spectroscopy, we demonstrate that the OPN ensemble exhibits not only characteristics of an extended and flexible polypeptide, as expected for an IDP, but also simultaneously those of globular proteins, in particular sigmoidal structural denaturation profiles.

The latter can result in a competition of solvent molecules with enzyme-bound water molecules and results in structural changes or denaturation (Ogino and Ishikawa 2001; Yang et al. 2004).

The truncated monomeric RIα 92 381) protein that contains the tandem CNB A and B domains, but lacks the highly helical N-terminal docking/dimerization (D/D) domain [32], was selected to further investigate determinants for thermal stability of RIα and the apparent structural conversion upon denaturation.

Although DARPins are already very stable molecules, molecular dynamics simulations, equilibrium denaturation experiments, structural studies, and recent NMR experiments suggested that the unfolding of the original C-terminal capping repeat (C-cap), taken from a natural ankyrin repeat protein, limits the stability of the initial DARPin design.

Thermal laser achieves tissue bonding by denaturation of structural proteins, which anneal and join when cooled.

Thus, CCT and the suite of chaperones that maintain protein homeostasis in Antarctic fishes provide novel opportunities for mechanistic analysis of cold denaturation using structural and biophysical strategies.

This indicates the residual presence of undefined structural elements after thermal denaturation of the antibodies, which agrees well with the observation that protein precipitation did not occur.