A possible explanation for this observation could be offered by mere structural considerations: culture in spheroids may provide an overall smaller cell surface accessible to CTL attack, as compared to monolayers, resulting in decreased activation of effector cells.
The contextual barriers involved four interrelated socio-structural factors: culture (i.e. shared practices and systems of belief), economic circumstances, social status, and gender.
This study shows that structured tissue culture substrates affects Ca2+ cycling and structural properties in cultured human iPSC-CM.
It is considered that highly porous nanofibrous mat with high surface area and nanosized roughness offers a biomimicking structure during cell culture, more structural space for accommodation and attachment and proliferation of cells, and enables the efficient exchange of nutrient and metabolic wastes.
However, the evolution of structural properties during culture, the relative contributions of the epidermis and dermis, and any correlation with tissue morphogenesis are not well known.
Cleveland Clinic wasn't built overnight, and there are other key structural and organizational culture assets.
The second is concerned with what Ellenbogen describes as "norm change," or shifting greater societal trends—socio-economic setbacks, gang culture, structural racism, mass incarceration ingrained in the system the teenage girl mentioned.
The continued performance failure of $167million reported loss in last three months of 2016 and a stagnant 4% growth of total users at Twitter is part of an underlying structural problem and culture at the company inability to move beyond its early foundations of a simple microblog.
This review identified several barriers, including: cost; culture; structural issues; situated-specific limitations; and population-specific limitations.
This step is fraught with complexity and the influence of, and socio-technical interactions among, physician factors, practice culture, structural factors, and patient factors [ 15].
