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If there is selection for secondary structures, one might expect higher structural constraint at paired than at unpaired sites.
A further caveat to the use of the BH3 peptides in isolation is their lack of secondary structure, which – in the absence of a structural constraint – precludes high-affinity interactions with their targets.
Results are reported in table 1. > -wrap-foot> All sequences were also submitted to I-TASSER using 2ZUO*b (from the rat crystal structure) as a constraint to determine the influence a structural constraint has on the modeling.
Seismic wave attenuation in this arc would be an important structural constraint to understand the current magma distribution and temperature structure.
CDPs 37, 129 and 284 do not take part in secondary structure, suggesting that they may be under functional rather than structural constraint.
In our quantitative models, we clarify the notion of structural constraint by quantifying how large must be a disadvantage for altering structure in order to outweigh the large benefit of escaping host immunity.
Bach's Goldberg Variations played in my head and on the page, showing me how structural constraint – limitations on freedom – might provoke artistic creativity, individuality, resonance.
A structural constraint is proposed for the acoustic optimization.
This structural constraint indicates that the Misaka block obducted onto the Honshu arc.
The structural constraint was set with the proximal edge marked as the fixed base.
The mountain environment is perceived today by vine-growers as a strong structural constraint.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com