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Equipoise may be strongly valid according to the study investigators, but clinicians whose patients are needed for such trials may not share this equipoise.
For example, if elevated mesolimbic dopamine transmission was firmly established to be the underlying cause of positive symptoms in schizophrenia patients, then rats with elevated mesolimbic dopamine would be a strongly valid model of the disease, even if this produced behaviors in the rats (eg, excessive locomotor activity) that are not homologous to positive symptoms in schizophrenia patients.
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"We strongly dispute any valid comparison and question the ability of tax experts you cite to make such a comparison without knowledge of the relevant facts".
For all of the talk about negotiating tactics, all sides have valid and strongly held views on the issues.
The point Mr. Hein is presumably trying to make — that the spectacles we gawk at in galleries are part of a larger social construct — is a valid one, strongly influenced by Dan Graham and various practitioners of Relational Aesthetics.
The traditional perturbation methods have many shortcomings, and they are not valid for strongly nonlinear dynamical systems.
There is one technique specific to the analysis of the synchronous state in a quite large class of network models that is valid for strongly coupled identical systems, namely the master stability function (MSF) approach.
This assumption is not valid for strongly nonlinear problems, such as turbulence, where nonlinear interactions rapidly redistribute energy resulting in the appearance of a broad continuous spectrum of amplitudes.
However, whereas the orbit-averaged equations of motion are valid for strongly hierarchical systems, they become inaccurate for triples with weaker hierarchies (e.g. Antonini and Perets 2012; Katz and Dong 2012; Naoz et al. 2013; Antonini et al. 2014; Antognini et al. 2014; Bode and Wegg 2014; Luo et al. 2016).
Austin McGary argued strongly that to be valid, the convert must also understand that baptism is for the forgiveness of sins.
Despite these, the magnitude of the observed associations is strongly suggestive of a valid relationship.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com