Sentence examples for strongly synergize from inspiring English sources

We recently reported that the IL-1 family cytokines, IL-1β and IL-18, strongly synergize with TNFα for IFNγ production in KG-1 cells, whereas the same cytokines alone have minimal effects on IFNγ production.

We show that Aurora B and Mps1 strongly synergize in the checkpoint.

Performing additional genetic interaction tests with Sxl indicates the two chromatin modifying systems can strongly synergize.

Moreover, PR-DUB and Sce strongly synergize to repress HOX genes.

dSfmbt and Scm co-occupy Polycomb response elements of target genes in Drosophila and they strongly synergize in the repression of these target genes, suggesting that the combined action of these two MBT proteins is crucial for Polycomb silencing.

Although it is well established that chemotherapeutic drugs and death ligands strongly synergize in various cell types, the respective mechanisms of sensitization or synergy are not always clear, or may differ from cell type to cell type.

In the same experiment, wild type Grb2 strongly synergized with Wnt3a.

Rather unexpectedly, salubrinal, a recently identified PP1 inhibitor capable to protect against ER stress in various model systems, strongly synergized with proteasome inhibitors to augment apoptotic death of different leukemic cell lines.

Our data showing that Grb2 strongly synergizes with CA-β-catenin suggest that it operates either downstream of, or in parallel with, β-catenin, rather than acting to stabilize the protein.

However, expression of FAK in HEK293 cells, while not affecting sTF activity on its own, strongly synergized with Wnt3a (Fig. 6D), and this signaling was completely abrogated by the dominant negative, double SH3 domain mutant Grb2, dSH3-Grb2 (Fig. 6E), suggesting that Grb2 lies downstream of FAK in this pathway.

Moreover, when used in combination, NVP-AEW541 and lapatinib strongly synergized in all cell lines at all concentrations assayed.